What is LYFGENIA™?

What if you had the ability to treat sickle cell disease from within, without a donor?

As a one-time treatment, LYFGENIA works by adding functional copies of the beta-globin genegeneA sequence of DNA responsible for controlling inherited traits to your blood stem cellsblood stem cellsAn immature cell that has the potential to develop into any blood cell type, including white blood cells, red blood cells, and platelets to help your body make anti-sickling hemoglobinhemoglobinA protein in your red blood cells that carries oxygen throughout your body, so that you can potentially decrease or stop experiencing vaso-occlusive events (VOEs)vaso-occlusive events (VOEs)In a LYFGENIA clinical study, VOEs were defined as any of the following events requiring evaluation at a medical facility: an episode of acute pain with no medically determined cause other than vaso-occlusion, lasting more than 2 hours, acute chest syndrome, acute hepatic sequestration, or acute splenic sequestration.

What else should I know about LYFGENIA?

No donor needed

For ages 12 years or older
with a history of vaso-occlusive
events (VOEs)

Designed to allow for the
production of anti-sickling
hemoglobin to potentially
decrease or stop vaso-occlusive
events (VOEs)

No donor needed

For ages 12 years or older with a history of vaso-occlusive events (VOEs)

Designed to allow for the production of anti-sickling hemoglobin to potentially decrease or stop vaso-occlusive events (VOEs)